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Literature summary for 2.10.1.1 extracted from

  • Nichols, J.D.; Xiang, S.; Schindelin, H.; Rajagopalan, K.V.
    Mutational analysis of Escherichia coli MoeA: two functional activities map to the active site cleft (2007), Biochemistry, 46, 78-86.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.10.1.1

Protein Variants

Protein Variants Comment Organism
D142N high activity in vitro Escherichia coli
D228A wild type activity in vitro Escherichia coli
D228N wild type activity in vitro Escherichia coli
D259A high activity in vitro Escherichia coli
D59A high activity in vitro Escherichia coli
D59N high activity in vitro Escherichia coli
delPhe53-Arg139 inactive in vivo, low activity in vitro Escherichia coli
E188A wild type activity in vitro Escherichia coli
E188Q wild type activity in vitro Escherichia coli
K275Q decreased activity in vitro Escherichia coli
K279Q low activity in vitro Escherichia coli
R137Q decreased activity in vitro Escherichia coli
R350A low activity in vitro Escherichia coli
S271A decreased activity in vitro Escherichia coli
S371W low activity in vitro Escherichia coli
T100A decreased activity in vitro Escherichia coli
T100W decreased activity in vitro Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenylyl-molybdopterin + molybdate + 4 H+ Escherichia coli
-
 molybdenum cofactor + AMP + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P12281 K-12
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenylyl-molybdopterin + molybdate + 4 H+
-
 Escherichia coli molybdenum cofactor + AMP + H2O
-
 ?

Synonyms

Synonyms Comment Organism
MoeA
-
 Escherichia coli

General Information

General Information Comment Organism
metabolism molybdenum cofactor biosynthesis Escherichia coli