Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + glycine | Mus musculus | - |
L-ornithine + guanidinoacetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + glycine | - |
Mus musculus | L-ornithine + guanidinoacetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AGAT | - |
Mus musculus |
arginine:glycine amidinotransferase | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme-deficient mice develop cardiac dysfunction. Enzyme-deficient mice have rescuable changes in body water and organ weights suggesting a role for creatine as a compatible osmolyte. Creatine-naive enzyme-deficient mice have haemodynamic impairment with low left ventricular systolic pressure and reduced inotropy, lusitropy, and contractile reserve | Mus musculus |