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Literature summary for 2.1.3.15 extracted from

  • Blanchard, C.; Chapman-Smith, A.; Wallace, J.; Waldrop, G.
    The biotin domain peptide from the biotin carboxyl carrier protein of Escherichia coli acetyl-CoA carboxylase causes a marked increase in the catalytic efficiency of biotin carboxylase and carboxyltransferase relative to free biotin (1999), J. Biol. Chem., 274, 31767-31769 .
    View publication on PubMed
Search for more literature for 2.1.3.15

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.16
-
 [biotin carboxyl-carrier protein 87]-N6-carboxybiotinyl-L-lysine pH and temperature not specified in the publication Escherichia coli
0.45
-
 [biotin carboxyl-carrier protein 87]-N6-biotinyl-L-lysine pH and temperature not specified in the publication Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine + acetyl-CoA Escherichia coli
-
 [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine + malonyl-CoA
-
 r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel affinity chromatography Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[biotin carboxyl-carrier protein 87]-N6-biotinyl-L-lysine + malonyl-CoA
-
 Escherichia coli [biotin carboxyl-carrier protein 87]-N6-carboxybiotinyl-L-lysine + acetyl-CoA
-
 r
[biotin carboxyl-carrier protein 87]-N6-carboxybiotinyl-L-lysine + acetyl-CoA
-
 Escherichia coli [biotin carboxyl-carrier protein 87]-N6-biotinyl-L-lysine + malonyl-CoA
-
 r
[biotin carboxyl-carrier protein]-N6-carboxybiotinyl-L-lysine + acetyl-CoA
-
 Escherichia coli [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine + malonyl-CoA
-
 r

Synonyms

Synonyms Comment Organism
acetyl-CoA carboxylase the enzyme consists of a biotin carboxylase activity, a biotin carboxyl carrier protein, and a carboxyltransferase activity Escherichia coli