Literature summary for 2.1.2.3 extracted from

Witkowska, D.; Cox, H.L.; Hall, T.C.; Wildsmith, G.C.; Machin, D.C.; Webb, M.E.
Analysis of substrate binding in individual active sites of bifunctional human ATIC (2018), Biochim. Biophys. Acta, 1866, 254-263 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	Homo sapiens	-	tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	-	Homo sapiens	tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	-	?

Synonyms

Synonyms	Comment	Organism
AICAR transformylase	-	Homo sapiens
AICARFT	-	Homo sapiens
ATIC	bifunctional enzyme with aminoimidazolecarboxamide ribonucleotide formyl transferase and inosine monophosphate cyclohydrolase activities	Homo sapiens

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Release 2023.1 (January 2023)