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Literature summary for 2.1.2.1 extracted from

  • Choi, M.
    Human serine hydroxymethyltransferase 2 (SHMT2) interacts with hnRNP D (2008), Genes Genomics, 30, 541-548.
No PubMed abstract available

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-serine + tetrahydrofolate Homo sapiens
-
glycine + 5,10-methylenetetrahydrofolate + H2O
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-serine + tetrahydrofolate
-
Homo sapiens glycine + 5,10-methylenetetrahydrofolate + H2O
-
?
additional information human serine hydroxymethyltransferase 2 binds specifically to heterogeneous nuclear ribonucleoprotein D Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
serine hydroxymethyltransferase 2
-
Homo sapiens
SHMT2
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Homo sapiens