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Literature summary for 2.1.1.B113 extracted from

  • Grogan, D.W.
    Cytosine methylation by the SuaI restriction-modification system: implications for genetic fidelity in a hyperthermophilic archaeon (2003), J. Bacteriol., 185, 4657-4661.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.B113

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Sulfolobus acidocaldarius the enzyme SuaI uses N4 methylation of the inner C to protect its recognition sequence (GGCC) from restriction ?
-
 ?
additional information Sulfolobus acidocaldarius DG185 the enzyme SuaI uses N4 methylation of the inner C to protect its recognition sequence (GGCC) from restriction ?
-
 ?
S-adenosyl-L-methionine + DNA containing the recognition sequence GGCC Sulfolobus acidocaldarius
-
 S-adenosyl-L-homocysteine + DNA containing the recognition sequence GGmCC
-
 ?
S-adenosyl-L-methionine + DNA containing the recognition sequence GGCC Sulfolobus acidocaldarius DG185
-
 S-adenosyl-L-homocysteine + DNA containing the recognition sequence GGmCC
-
 ?

Organism

Organism UniProt Comment Textmining
Sulfolobus acidocaldarius
-
-
-
Sulfolobus acidocaldarius DG185
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Sulfolobus acidocaldarius

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme SuaI uses N4 methylation of the inner C to protect its recognition sequence (GGCC) from restriction Sulfolobus acidocaldarius ?
-
 ?
additional information the enzyme SuaI uses N4 methylation of the inner C to protect its recognition sequence (GGCC) from restriction Sulfolobus acidocaldarius DG185 ?
-
 ?
S-adenosyl-L-methionine + DNA containing the recognition sequence GGCC
-
 Sulfolobus acidocaldarius S-adenosyl-L-homocysteine + DNA containing the recognition sequence GGmCC
-
 ?
S-adenosyl-L-methionine + DNA containing the recognition sequence GGCC
-
 Sulfolobus acidocaldarius DG185 S-adenosyl-L-homocysteine + DNA containing the recognition sequence GGmCC
-
 ?

General Information

General Information Comment Organism
physiological function the SuaI system uses N4-methylation of the inner C to block cleavage of its recognition site(GGCC), thereby avoiding the creation of G/T mismatches by spontaneous deamination at extremely high temperature Sulfolobus acidocaldarius