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Literature summary for 2.1.1.80 extracted from

  • Perez, E.; West, A.H.; Stock, A.M.; Djordjevic, S.
    Discrimination between different methylation states of chemotaxis receptor Tar by receptor methyltransferase CheR (2004), Biochemistry, 43, 953-961.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli at 30°C under the control of The T7 polymerase Salmonella enterica

Protein Variants

Protein Variants Comment Organism
DELTA1-19 activity is slightly reduced Salmonella enterica
K46A moderately reduced activity Salmonella enterica
R47A mutant protein does not express well, all of the CheR protein is found in inclusion bodies Salmonella enterica
R53A methyltransferase activity is 4% of the wild-type activity Salmonella enterica
R56A moderately reduced activity Salmonella enterica
R57A mutant protein does not express well, all of the CheR protein is found in inclusion bodies Salmonella enterica
R59A moderately reduced activity Salmonella enterica

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + [chemotaxis receptor Tar]-L-glutamate
-
Salmonella enterica S-adenosyl-L-homocysteine + [chemotaxis receptor Tar]-L-glutamate methyl ester
-
?

Synonyms

Synonyms Comment Organism
CheR
-
Salmonella enterica