Literature summary for 2.1.1.8 extracted from

Aschenbach, J.R.; Schwelberger, H.G.; Ahrens, F.; Fuerll, B.; Gaebel, G.
Histamine inactivation in the colon of pigs in relationship to abundance of catabolic enzymes (2006), Scand. J. Gastroenterol., 41, 712-719.

Search for more literature for 2.1.1.8

Application

Application	Comment	Organism
degradation	higher HMT activity seems to be linked to reduced histamine catabolism, percentage of catabolized histamine is not correlated to individual mannitol fluxes and appears to be independent of paracellular permeability	Sus scrofa

Organism

Organism	UniProt	Comment	Textmining
Sus scrofa	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
colon	HMT activity comparable to activity in the jejunum	Sus scrofa	-
epithelium	-	Sus scrofa	-
jejunum	HMT activity comparable to activity in the colon	Sus scrofa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + histamine	given a negative correlation between diamine oxidase and HMT activities, the fraction of catabolized histamine decreases with increasing HMT activity	Sus scrofa	S-adenosyl-L-homocysteine + Ntau-methylhistamine	-	?

Synonyms

Synonyms	Comment	Organism
HMT	-	Sus scrofa

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Release 2023.1 (January 2023)