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Literature summary for 2.1.1.8 extracted from

  • Rhim, H.; Choi, M.U.
    Purification and general characterization of rat brain histamine N-methyltransferase (1989), Hanguk Saenghwahakhoe Chi, 22, 455-461.
No PubMed abstract available
Search for more literature for 2.1.1.8

Activating Compound

Activating Compound Comment Organism Structure
iodoacetamide activation Rattus norvegicus
iodoacetic acid activation Rattus norvegicus
Succinic anhydride activation Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
iodoacetamide activation Rattus norvegicus
N-ethylmaleimide
-
 Rattus norvegicus
p-chloromercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.012
-
 histamine
-
 Rattus norvegicus
0.04
-
 S-adenosyl-L-methionine
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.004
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histamine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + Ntau-methylhistamine
-
 ?