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Literature summary for 2.1.1.77 extracted from

  • Saito, H.; Yamashita, M.; Ogasawara, M.; Yamada, N.; Niisato, M.; Tomoyasu, M.; Deguchi, H.; Tanita, T.; Ishida, K.; Sugai, T.; Yamauchi, K.
    Chaperone protein L-isoaspartate (D-aspartyl) O-methyltransferase as a novel predictor of poor prognosis in lung adenocarcinoma (2016), Hum. Pathol., 50, 1-10 .
    View publication on PubMed
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Application

Application Comment Organism
medicine strong enzyme expression is a predictive marker of poor prognosis for surgically resected lung adenocarcinoma Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate Homo sapiens
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung adenocarcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate
-
 Homo sapiens S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Synonyms

Synonyms Comment Organism
chaperone protein L-isoaspartate (D-aspartyl) O-methyltransferase
-
 Homo sapiens
PIMT
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme expression is increased in patients with advanced stages of lung adenocarcinoma up