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Literature summary for 2.1.1.77 extracted from

  • Brennan, T.V.; Anderson, J.W.; Jia, Z.; Waygood, E.B.; Clarke, S.
    Repair of spontaneously deamidated HPr phosphocarrier protein catalyzed by the L-isoaspartate-(D-aspartate) O-methyltransferase (1994), J. Biol. Chem., 269, 24586-24595.
    View publication on PubMed
Search for more literature for 2.1.1.77

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00358
-
 histidine phosphocarrier protein-1 (isoAsp-38)
-
 Homo sapiens
0.0068
-
 VYP-L-isoAsp-GA
-
 Homo sapiens
0.0155
-
 YVS-isoAsp-GHG
-
 Homo sapiens
0.0229
-
 T1-isoAsp-12
-
 Homo sapiens
0.0274
-
 V2-isoAsp-12
-
 Homo sapiens
0.0975
-
 V4-isoAsp-38
-
 Homo sapiens
0.197
-
 HPr-2 (isoAsp-12,-38)
-
 Homo sapiens
0.339
-
 T4-isoAsp-38
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + protein L-isoaspartate Homo sapiens
-
 S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information native E. coli histidine phosphocarrier protein is no substrate Homo sapiens ?
-
 ?
S-adenosyl-L-methionine + histidine phosphocarrier protein (isoAsp-38)
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + histidine phosphocarrier protein-1 (isoAsp-38)
-
 Homo sapiens ?
-
 ?
S-adenosyl-L-methionine + histidine phosphocarrier protein-2 (isoAsp-12,-38)
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + HPr-2 (isoAsp-12,-38)
-
 Homo sapiens ?
-
 ?
S-adenosyl-L-methionine + KMK-isoD-TDSEEEIR
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + protein L-isoaspartate
-
 Homo sapiens S-adenosyl-L-homocysteine + protein L-isoaspartate alpha-methyl ester
-
 ?
S-adenosyl-L-methionine + T1-isoAsp-12
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + T4-isoAsp-38
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + V2-isoAsp-12
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + V4-isoAsp-38
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + VYP-L-isoAsp-GA
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?
S-adenosyl-L-methionine + YVS-isoAsp-GHG
-
 Homo sapiens S-adenosyl-L-homocysteine + ?
-
 ?