Literature summary for 2.1.1.72 extracted from

Simala-Grant, J.L.; Lam, E.; Keelan, M.; Taylor, D.E.
Characterization of the DNA adenine 5'-GATC-3' methylase HpyIIIM from Helicobacter pylori (2004), Curr. Microbiol., 49, 47-54.

Search for more literature for 2.1.1.72

Cloned(Commentary)

Cloned (Comment)	Organism
gene jhp0085, DNA sequence determination	Helicobacter pylori

Protein Variants

Protein Variants	Comment	Organism
additional information	mutational inactivation of the enzyme does not influence the mismatch repair, the adherence of the bacterium to host cells, e.g. HEp-2 cells, or the fitness of the bacterial cell	Helicobacter pylori

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + DNA adenine	Helicobacter pylori	enzyme is not important in mismatch repair and for adherence of the bacterium to host cells, e.g. HEp-2 cells	S-adenosyl-L-homocysteine + DNA 6-methylaminopurine	-	?

Organism

Organism	UniProt	Comment	Textmining
Helicobacter pylori	-	diverse strains, overview	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + DNA adenine	-	Helicobacter pylori	S-adenosyl-L-homocysteine + DNA 6-methylaminopurine	-	?
S-adenosyl-L-methionine + DNA adenine	enzyme is not important in mismatch repair and for adherence of the bacterium to host cells, e.g. HEp-2 cells	Helicobacter pylori	S-adenosyl-L-homocysteine + DNA 6-methylaminopurine	-	?

Synonyms

Synonyms	Comment	Organism
DNA adenine 5'-GATC-3' methylase	-	Helicobacter pylori
HpyIIIM	-	Helicobacter pylori

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Release 2023.1 (January 2023)