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Literature summary for 2.1.1.7 extracted from

  • Li, W.; Zhang, F.; Wu, R.; Jia, L.; Li, G.; Guo, Y.; Liu, C.; Wang, G.
    A novel N-methyltransferase in Arabidopsis appears to feed a conserved pathway for nicotinate detoxification among land plants and is associated with lignin biosynthesis (2017), Plant Physiol., 174, 1492-1504 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0387
-
 nicotinate pH 7.5, 28°C Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9SCP7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information product N-methylnicotinate accumulates predominantly in inflorescence tissues Arabidopsis thaliana
-
silique
-
 Arabidopsis thaliana
-
stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + nicotinate
-
 Arabidopsis thaliana S-adenosyl-L-homocysteine + N-methylnicotinate
-
 ?

Synonyms

Synonyms Comment Organism
At3g53140
-
 Arabidopsis thaliana
NANMT
-
 Arabidopsis thaliana
T4D2.70
-
 Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.52
-
 nicotinate pH 7.5, 28°C Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function homozygous mutant lines show marked reductions in N-methylnicotinate accumulation in inflorescence tissues, whereas the levels of nicotinate, glucosylated nicotinate, nicotinate mononucleotide, and NAD are increased. Overexpressing lines have higher N-methylnicotinate content and lower nicotinate, glucosylated nicotinate, nicotinate mononucleotide, and NAD contents Arabidopsis thaliana

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
91
-
 nicotinate pH 7.5, 28°C Arabidopsis thaliana