Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.68 extracted from

  • Wiens, B.; De Luca, V.
    Molecular and biochemical characterization of a benzenoid/phenylpropanoid meta/para-O-methyltransferase from Rauwolfia serpentina roots (2016), Phytochemistry, 132, 5-15 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene OMT1, DNA and amino acid sequence determination and analysis, phylogenetic analysis Rauvolfia serpentina
gene OMT3, DNA and amino acid sequence determination and analysis, phylogenetic analysis Rauvolfia serpentina

Organism

Organism UniProt Comment Textmining
Rauvolfia serpentina A0A1I9RGJ4
-
-
Rauvolfia serpentina A0A1I9RGJ6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Rauvolfia serpentina
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme RsOMT1 converts 3,5-dimethoxy-4-hydroxycinnamic, caffeic and 3,4,5-trihydroxybenzoic acids to trimethoxycinnamic-, ferulic/isoferulic- and 3-methoxy-4,5-dihydroxybenzoic, or 4-methoxy-3,5-dihydroxybenzoic acids, respectively, when supplied with these substrates Rauvolfia serpentina ?
-
-
additional information enzyme RsOMT3 only converts caffeic acid to ferulic acid. The enzyme shows considerable promiscuity with respect to various flavonoid substrates that it accepts Rauvolfia serpentina ?
-
-

Synonyms

Synonyms Comment Organism
benzenoid/phenylpropanoid meta/para-O-methyltransferase
-
Rauvolfia serpentina
OMT
-
Rauvolfia serpentina
RsOMT1
-
Rauvolfia serpentina
RsOMT3
-
Rauvolfia serpentina

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
Rauvolfia serpentina

General Information

General Information Comment Organism
evolution transcriptome and metabolome analyses of Rauwolfia serpentina roots allow the identification of 7 candidate O-methytransferase (OMT) genes that might be associated with the formation of 3,4,5-trimethoxybenzoate and 3,4,5-trimethoxycinnamate. RsOMT1 is a member of the caffeoyl CoA-OMT-like family of genes Rauvolfia serpentina
evolution transcriptome and metabolome analyses of Rauwolfia serpentina roots allow the identification of 7 candidate O-methytransferase (OMT) genes that might be associated with the formation of 3,4,5-trimethoxybenzoate and 3,4,5-trimethoxycinnamate. RsOMT3 is a member of the caffeic acid-OMT-like family of genes Rauvolfia serpentina
metabolism involvement of RsOMT1 and RsOMT3 in the assembly of trimethoxybenzoic and trimethoxycinnamic acids Rauvolfia serpentina
physiological function the monoterpenoid indole alkaloids, reserpine and rescinnamine contain 3,4,5-trimethoxybenzoate or 3,4,5-trimethoxycinnamate, respectively, within their structures and they accumulate in different plant organs and particularly within roots of Rauwolfia serpentina. This plant also accumulates acylated sugars substituted with 3,4,5-trimethoxybenzoate and 3,4,5-trimethoxycinnamate Rauvolfia serpentina