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Literature summary for 2.1.1.67 extracted from
- Genome-wide association study for the genetic determinants of thiopurine methyltransferase protein expression in human livers and racial differences (2023), Pharm. Res., 40, 2525-2531.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | hepatic TPMT protein expression is significantly lower in subjects carrying the TPMT*3A, TPMT*3C, and TPMT*24 alleles compared to non-carriers. European ancestry is associated with significantly higher hepatic TPMT protein expression than African ancestry, independent of known TPMT variants | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thiopurine methyltransferase | - |
Homo sapiens |
| TPMT | - |
Homo sapiens |
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Release 2026.1 (March 2026)
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