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Literature summary for 2.1.1.67 extracted from

  • Uehara, S.; Uno, Y.; Yamazaki, H.
    Molecular cloning and tissue distribution of marmoset thiopurine S-methyltransferase (2020), Drug Metab. Pharmacokinet., 35, 475-478.
    View publication on PubMed
Search for more literature for 2.1.1.67

Cloned(Commentary)

Cloned (Comment) Organism
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 Callithrix jacchus
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 Homo sapiens
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 Mus musculus
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 Oryctolagus cuniculus
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 Pan troglodytes
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 Pongo pygmaeus
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 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Callithrix jacchus F6PNF2
-
-
Homo sapiens P51580
-
-
Mus musculus O55060
-
-
Oryctolagus cuniculus Q3BCQ8
-
-
Pan troglodytes Q3BCR8
-
-
Pongo pygmaeus Q5RBJ3
-
-
Rattus norvegicus Q9Z0T0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain low mRNA level Callithrix jacchus
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kidney among the five marmoset tissue types analyzed, marmoset thiopurine S-methyltransferase mRNA is most abundant in kidney and liver Callithrix jacchus
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liver among the five marmoset tissue types analyzed, marmoset thiopurine S-methyltransferase mRNA is most abundant in kidney and liver Callithrix jacchus
-
lung low mRNA level Callithrix jacchus
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small intestine low mRNA level Callithrix jacchus
-

Synonyms

Synonyms Comment Organism
TPMT
-
 Callithrix jacchus
TPMT
-
 Homo sapiens
TPMT
-
 Mus musculus
TPMT
-
 Rattus norvegicus
TPMT
-
 Oryctolagus cuniculus
TPMT
-
 Pan troglodytes
TPMT
-
 Pongo pygmaeus

General Information

General Information Comment Organism
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs. Callithrix jacchus and human TPMT are similar at the molecular level Callithrix jacchus
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs. Callithrix jacchus and human TPMT are similar at the molecular level Homo sapiens
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs Mus musculus
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs Rattus norvegicus
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs Oryctolagus cuniculus
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs Pan troglodytes
evolution Callithrix jacchus thiopurine S-methyltransferase (TPMT) is phylogenetically closer to other primate orthologs than to its pig, dog, rabbit, or rodent orthologs Pongo pygmaeus
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Callithrix jacchus
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Homo sapiens
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Mus musculus
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Rattus norvegicus
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Oryctolagus cuniculus
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Pan troglodytes
additional information the enzyme plays roles in the metabolism of widely used anticancer and anti-inflammatory drugs Pongo pygmaeus