Literature summary for 2.1.1.67 extracted from

Pecher, D.; Dokupilova, S.; Zelinkova, Z.; Peppelenbosch, M.; Mikusova, V.; Mikus, P.
Determination of thiopurine S-methyltransferase activity by hydrophilic interaction liquid chromatography hyphenated with mass spectrometry (2017), J. Pharm. Biomed. Anal., 142, 244-251 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
S-adenosyl-L-methionine + a thiopurine	Homo sapiens	-	S-adenosyl-L-homocysteine + a thiopurine S-methylether	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + 6-mercaptopurine	-	Homo sapiens	S-adenosyl-L-homocysteine + 6-methylmercaptopurine	-	?
S-adenosyl-L-methionine + 6-thioguanine	-	Homo sapiens	S-adenosyl-L-homocysteine + 6-methylthioguanine	-	?
S-adenosyl-L-methionine + a thiopurine	-	Homo sapiens	S-adenosyl-L-homocysteine + a thiopurine S-methylether	-	?

Synonyms

Synonyms	Comment	Organism
TPMT	-	Homo sapiens

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Release 2023.1 (January 2023)