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Literature summary for 2.1.1.67 extracted from
- Optimising azathioprine treatment: determination of thiopurine methyltransferase activity and thiopurine metabolites (2009), An. Pediatr. (Barc. ), 70, 126-131.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | determination of TPMT and monitoring of thiopurine metabolites allows azathioprine treatment to be optimised | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + 6-thiopurine | - |
Homo sapiens | S-adenosyl-L-homocysteine + 6-methylthiopurine | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| thiopurine methyltransferase | - |
Homo sapiens |
| TPMT | - |
Homo sapiens |
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