Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | - |
Homo sapiens | - |
LN-18 cell | - |
Homo sapiens | - |
LN-229 cell | - |
Homo sapiens | - |
Tu-113 cell | - |
Homo sapiens | - |
Tu-132 cell | - |
Homo sapiens | - |
U-87MG cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MGMT | - |
Homo sapiens |
O6-methylguanine-DNA methyltransferase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | neither short-term (24 h) nor long-term changes (7 weeks) in S-adenosyl-L-methionine/S-adenosylhomocysteine ratio alter global or MGMT promoter methylation, however, experimentally elevated S-adenosylhomocysteine levels significantly decrease MGMT mRNA levels by more than 50% | down |