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Literature summary for 2.1.1.60 extracted from

  • Morino, H.; Kawamoto, T.; Miyake, M.; Kakimoto, Y.
    Purification and properties of calmodulin-lysine N-methyltransferase from rat brain cytosol (1987), J. Neurochem., 48, 1201-1208.
    View publication on PubMed
Search for more literature for 2.1.1.60

Activating Compound

Activating Compound Comment Organism Structure
Ca2+ stimulation Rattus norvegicus
Mn2+ stimulation Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00002
-
 Octopus calmodulin
-
 Rattus norvegicus
0.0008
-
 S-adenosyl-L-methionine
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ stimulation Rattus norvegicus
Mn2+ stimulation Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
57000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + calmodulin L-lysine octopus calmodulin Rattus norvegicus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine enzyme methylates a specific lysine residue of octopus calmodulin ?
S-adenosyl-L-methionine + calmodulin L-lysine octopus calmodulin Rattus norvegicus S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine formation of epsilon-N-mono-, epsilon-N-di- and epsilon-N-trimethyllysine, the labelled N-methyllysine lies in the 107-126 peptide ?
S-adenosyl-L-methionine + Octopus calmodulin L-lysine
-
 Rattus norvegicus S-adenosyl-L-homocysteine + Octopus calmodulin N6-methyl-L-lysine
-
 r

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8.5
-
 Rattus norvegicus