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Literature summary for 2.1.1.6 extracted from

  • Poor, M.; Zrinyi, Z.; K?szegi, T.
    Structure related effects of flavonoid aglycones on cell cycle progression of HepG2 cells Metabolic activation of fisetin and quercetin by catechol-O-methyltransferase (COMT) (2016), Biomed. Pharmacother., 83, 998-1005 .
    View publication on PubMed

Application

Application Comment Organism
medicine inhibition of catechol-O-methyltransferase enzyme by entacapone decreases the antiproliferative effects of fisetin and quercetin on Hep-G2 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
entacapone
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P21964
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
Homo sapiens
-