Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
24000 | - |
isoform S-COMT, SDS-PAGE | Rattus norvegicus |
28000 | - |
isoform L-COMT, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
heart | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
hepatocyte | - |
Rattus norvegicus | - |
kidney | S-COMT isoforms are highly and preferentially expressed in kidney | Rattus norvegicus | - |
liver | S-COMT isoforms are highly expressed in liver, liver displays a very weak expression of L-COMT isoforms | Rattus norvegicus | - |
lung | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
additional information | both of the L-COMT isoforms are found in all of the tissues examined except the heart, which expresses only the most acidic form, and the kidney, which expresses only the most basic form | Rattus norvegicus | - |
spleen | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
submandibular salivary gland | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
testis | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
thymus | L-COMT is the predominant enzyme form | Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
L-COMT | large variant of catechol O-methyltransferase | Rattus norvegicus |
S-COMT | small variant of catechol O-methyltransferase | Rattus norvegicus |