Activating Compound | Comment | Organism | Structure |
---|---|---|---|
importin-alpha | enhances specific binding of the enzyme to RNA, enhances RNA modification activity in vivo and in vitro | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of full length enzyme and truncated enzyme in yeast and in HeLa cells, His-tagged, as GFP-fusion protein, or cMyc-tagged | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GpppG | inhibits binding of the enzyme to RNA | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | GFP-fusion protein analysis | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + G(5')pppR-RNA | - |
Homo sapiens | S-adenosyl-L-homocysteine + m7G(5')pppR-RNA | - |
? |