Literature summary for 2.1.1.56 extracted from

Tsukamoto, T.; Shibagaki, Y.; Niikura, Y.; Mizumoto, K.
Cloning and characterization of three human cDNAs encoding mRNA (guanine-7-)-methyltransferase, an mRNA cap methylase (1998), Biochem. Biophys. Res. Commun., 251, 27-34.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Saccharomyces cerevisiae, His-tagged, amino acid sequence analysis	Saccharomyces cerevisiae
expression of 2 different variants, each with and without His-tag, in Escherichia coli, amino acid sequence analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Saccharomyces cerevisiae	P32783	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA	-	Homo sapiens	S-adenosyl-L-homocysteine + m7G(5')pppR-RNA	-	?
S-adenosyl-L-methionine + G(5')pppR-RNA	-	Saccharomyces cerevisiae	S-adenosyl-L-homocysteine + m7G(5')pppR-RNA	-	?

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Homo sapiens
37	-	assay at	Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8	-	assay at	Homo sapiens
8	-	assay at	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)