Literature summary for 2.1.1.56 extracted from

Pugh, C.S.; Borchardt, R.T.; Stone, H.O.
Inhibition of Newcastle disease virion messenger RNA (guanine-7-)-methyltransferase by analogues of S-adenosylhomocysteine (1977), Biochemistry, 16, 3928-3932.

Search for more literature for 2.1.1.56

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	no inhibition by S-uridinyl-L-homocysteine, S-cytidinyl-L-homocysteine; S-guanosyl-L-homocysteine	Avian orthoavulavirus 1
S-(3-deazaadenosyl)-L-homocysteine	strong	Avian orthoavulavirus 1
S-(8-azaadenosyl)-L-homocysteine	moderate	Avian orthoavulavirus 1
S-Adenosyl-D-homocysteine	moderate	Avian orthoavulavirus 1
S-adenosyl-L-homocysteine	product inhibition, competitive	Avian orthoavulavirus 1
S-Adenosyl-L-homocysteine structural analogues	-	Avian orthoavulavirus 1
S-Adenosyl-L-homocysteine sulfone	strong	Avian orthoavulavirus 1
S-adenosyl-L-homocysteine sulfoxide	strong	Avian orthoavulavirus 1
S-Aristeromycinyl-L-homocysteine	-	Avian orthoavulavirus 1
S-Tubercidinyl-L-homocysteine	strong	Avian orthoavulavirus 1

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
viral nucleocapsid	-	Avian orthoavulavirus 1	19013	-

Organism

Organism	UniProt	Comment	Textmining
Avian orthoavulavirus 1	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
S-adenosyl-L-methionine + G(5')pppR-RNA	-	Avian orthoavulavirus 1	S-adenosyl-L-homocysteine + m7G(5')pppR-RNA	R may be guanosine or adenosine, mRNA containing an N7-methylguanine cap	?

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Release 2023.1 (January 2023)