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Literature summary for 2.1.1.5 extracted from

  • Zhang, Y.; Zhu, T.; Wang, L.; Pan, Y.; Zhang, S.
    Homocysteine homeostasis and betaine-homocysteine S-methyltransferase expression in the brain of hibernating bats (2013), PLoS ONE, 8, e85632.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Myotis ricketti A0A059PVS2
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Source Tissue

Source Tissue Comment Organism Textmining
basal ganglion BHMT expression is observed in the amygdala of basal ganglia and the cerebral cortex where BHMT levels are clearly elevated during torpor Myotis ricketti
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brain
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Myotis ricketti
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cerebral cortex BHMT expression is observed in the amygdala of basal ganglia and the cerebral cortex where BHMT levels are clearly elevated during torpor Myotis ricketti
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General Information

General Information Comment Organism
physiological function in hybernating bats, homocysteine level does not elevate in brains, despite declining vitamin B levels. At low levels of vitamin B6 and B12, no change in total expression level of methionine synthase and cystathionine beta-synthase is found, but a 1.85fold increase in the expression of the coenzyme-independent betaine-homocysteine S-methyltransferase Myotis ricketti