Literature summary for 2.1.1.5 extracted from

Picha, J.; Vanek, V.; Budesinsky, M.; Mladkova, J.; Garrow, T.A.; Jiracek, J.
The development of a new class of inhibitors for betaine-homocysteine S-methyltransferase (2013), Eur. J. Med. Chem., 65, 256-275.

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Inhibitors

Inhibitors	Comment	Organism	Structure
5-(3-amino-3-carboxy-propylsulfanyl)-pentanoic acid	-	Homo sapiens
5-[3-(R,S)-3-amino-3-(hydroxyphosphorylpropyl)sulfanyl]-3,3-dimethylpentanoic acid	-	Homo sapiens
5-[3-(R,S)-3-amino-3-(hydroxyphosphorylpropyl)sulfanyl]pentanoic acid	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q93088	-	-

Synonyms

Synonyms	Comment	Organism
BHMT1	-	Homo sapiens

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.000093	-	pH not specified in the publication, temperature not specified in the publication	Homo sapiens	5-(3-amino-3-carboxy-propylsulfanyl)-pentanoic acid
0.0011	-	pH not specified in the publication, temperature not specified in the publication	Homo sapiens	5-[3-(R,S)-3-amino-3-(hydroxyphosphorylpropyl)sulfanyl]-3,3-dimethylpentanoic acid
0.005	-	pH not specified in the publication, temperature not specified in the publication	Homo sapiens	5-[3-(R,S)-3-amino-3-(hydroxyphosphorylpropyl)sulfanyl]pentanoic acid

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Release 2023.1 (January 2023)