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Literature summary for 2.1.1.5 extracted from

  • Ji, C.; Shinohara, M.; Vance, D.; Than, T.A.; Ookhtens, M.; Chan, C.; Kaplowitz, N.
    Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver (2008), Alcohol. Clin. Exp. Res., 32, 1049-1058.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine effect of extrahepatic expression of homo sapiens betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver is shown in transgenic mice Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information betaine-homocysteine methyltransferase transgenic (Tg) mice are generated. BHMT transgenic mice are resistant to alcohol or high methionine low folate diet-induced hyperhomocysteinemia and liver steatosis indicating that peripheral metabolism of homocysteine protects the liver without a direct effect of BHMT in the liver Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
betaine-homocysteine S-methyltransferase
-
Homo sapiens
BHMT
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Homo sapiens