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Literature summary for 2.1.1.37 extracted from
- Rice cytosine DNA methyltransferases - gene expression profiling during reproductive development and abiotic stress (2009), FEBS J., 276, 6301-6311.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene MET1B or MET1-2, phylogenetic analysis, microarray-based gene expression profile of all 10 MTases during 22 stages and tissues that include 14 stages of reproductive development and five vegetative tissues together with three stresses, cold, salt and dehydration stress, revealing specific windows of MTase activity during panicle and seed development, overview | Oryza sativa |
| gene OsCMT1, phylogenetic analysis, microarray-based gene expression profile of all 10 MTases during 22 stages and tissues that include 14 stages of reproductive development and five vegetative tissues together with three stresses, cold, salt and dehydration stress, revealing specific windows of MTase activity during panicle and seed development, overview | Oryza sativa |
| gene Zmt3, phylogenetic analysis, microarray-based gene expression profile of all 10 MTases during 22 stages and tissues that include 14 stages of reproductive development and five vegetative tissues together with three stresses, cold, salt and dehydration stress, revealing specific windows of MTase activity during panicle and seed development, overview | Oryza sativa |
| phylogenetic analysis, microarray-based gene expression profile of all 10 MTases during 22 stages and tissues that include 14 stages of reproductive development and five vegetative tissues together with three stresses, cold, salt and dehydration stress, revealing specific windows of MTase activity during panicle and seed development, overview | Oryza sativa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + S-adenosyl-L-methionine | Oryza sativa | - |
DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? |  |
| additional information | Oryza sativa | MTase performs two basic kinds of methylation activities: maintenance methylation, i.e. addition of methyl groups to cytosines of a hemimethylated DNA after DNA replication, and de novo methylation, i.e. methylation of cytosines in nonmethylated DNA | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Oryza sativa | B1Q3J6 | MET1B or MET1-2; subsp. japonica, encodes a total of 10 genes that contain the highly conserved MTase catalytic domain | - |
| Oryza sativa | B9FJ44 | subsp. japonica, encodes a total of 10 genes that contain the highly conserved MTase catalytic domain | - |
| Oryza sativa | Q10C15 | subsp. japonica, encodes a total of 10 genes that contain the highly conserved MTase catalytic domain | - |
| Oryza sativa | Q10SU5 | Zmt3; subsp. japonica, encodes a total of 10 genes that contain the highly conserved MTase catalytic domain | - |
| Oryza sativa | Q8H854 | CMT1; subsp. japonica, encodes a total of 10 genes that contain the highly conserved MTase catalytic domain | - |
| Oryza sativa | Q8SBB4 | subsp. japonica, encodes a total of 10 genes that contain the highly conserved MTase catalytic domain | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | microarray-based gene expression profile of all 10 MTases during 22 stages and tissues that include 14 stages of reproductive development and five vegetative tissues together with three stresses, cold, salt and dehydration stress, revealing specific windows of MTase activity during panicle and seed development, overview | Oryza sativa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + S-adenosyl-L-methionine | - |
Oryza sativa | DNA containing 5-methylcytosine + S-adenosyl-L-homocysteine | - |
? | |
| additional information | MTase performs two basic kinds of methylation activities: maintenance methylation, i.e. addition of methyl groups to cytosines of a hemimethylated DNA after DNA replication, and de novo methylation, i.e. methylation of cytosines in nonmethylated DNA | Oryza sativa | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | domain structures of isozymes, overview | Oryza sativa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CMT1 | - |
Oryza sativa |
| cytosine DNA methyltransferase | - |
Oryza sativa |
| cytosine DNA MTase | - |
Oryza sativa |
| MET1B | - |
Oryza sativa |
| More | four main subfamilies of MTases exist in plants | Oryza sativa |
| More | in plants exist four main subfamilies of MTases | Oryza sativa |
| Zmt3 | - |
Oryza sativa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| S-adenosyl-L-methionine | - |
Oryza sativa | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | MTases play a role in the epigenetic process affecting genome activity during reproductive development and stress | Oryza sativa |
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