Cloned (Comment) | Organism |
---|---|
expressed in S2 cells | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleosome | - |
Drosophila melanogaster | 786 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Drosophila melanogaster | the proteolytic degradation of the enzyme is controlled by the SCFSlimb ligase complex | ? | - |
? | |
S-adenosyl-L-methionine + a [histone H4]-L-lysine20 | Drosophila melanogaster | - |
S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | Q9VFK6 | - |
- |
Purification (Comment) | Organism |
---|---|
phosphoprotein column chromatography | Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the proteolytic degradation of the enzyme is controlled by the SCFSlimb ligase complex | Drosophila melanogaster | ? | - |
? | |
S-adenosyl-L-methionine + a [histone H4]-L-lysine20 | - |
Drosophila melanogaster | S-adenosyl-L-homocysteine + a [histone H4]-N6-methyl-L-lysine20 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 100000, SDS-PAGE | Drosophila melanogaster |
Synonyms | Comment | Organism |
---|---|---|
histone H4-K20 methyltransferase | - |
Drosophila melanogaster |
KMT5a | - |
Drosophila melanogaster |
Pr-Set7 | - |
Drosophila melanogaster |
SET8 | - |
Drosophila melanogaster |
SETD8 | - |
Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
physiological function | Slimb-mediated enzyme proteolysis is a critical regulatory mechanism required for proper interphase chromatin organization at G1/S transition | Drosophila melanogaster |