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Literature summary for 2.1.1.355 extracted from

  • Lee, J.E.; Park, S.Y.; Han, P.L.
    Aging-dependent downregulation of SUV39H1 histone methyltransferase increases susceptibility to stress-induced depressive behavior (2021), Mol. Neurobiol., 58, 6427-6442.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus O54864
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-

Synonyms

Synonyms Comment Organism
SUV39H1 histone methyltransferase
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Mus musculus

Expression

Organism Comment Expression
Mus musculus aged mice show decreased expression of SUV39H1 histone methyltransferase in the hippocampus down
Mus musculus rosmarinic acid increases SUV39H1 expression up

General Information

General Information Comment Organism
malfunction the siRNA-mediated knockdown of SUV39H1 increases Mkp-1 expression and suppresses p-CREB and Bdnf expression in HT22 cells and in the hippocampus of mice Mus musculus