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Literature summary for 2.1.1.355 extracted from
- Histone methyltransferases SUV39H1 and G9a and DNA methyltransferase DNMT1 in penumbra neurons and astrocytes after photothrombotic stroke (2021), Int. J. Mol. Sci., 22, 12483.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| A-366 | the inhibitor protects penumbra cells from apoptosis and reduces the volume of photothrombotic stroke-induced cerebral infarction | Rattus norvegicus | |
| BIX01294 | the inhibitor protects penumbra cells from apoptosis and reduces the volume of photothrombotic stroke-induced cerebral infarction | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| histone methyltransferases G9a | - |
Rattus norvegicus |
| histone methyltransferases SUV39H1 | - |
Rattus norvegicus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rattus norvegicus | an increase in the level of SUV39H1 in the penumbra at 24 h after photothrombotic stroke | up |
| Rattus norvegicus | G9a is overexpressed at 4 and 24 h after photothrombotic stroke | up |
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