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Literature summary for 2.1.1.355 extracted from
- Effect of SUV39H1 histone methyltransferase knockout on expression of differentiation-associated genes in HaCaT keratinocytes (2020), Cells, 9, 2628.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O43463 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HaCaT cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| H3K9 histone methyltransferase | - |
Homo sapiens |
| SUV39H1 histone methyltransferase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | SUV39H1 knockout causes a marked decrease in the level of H3K9me3 and results in altered expression of some of the examined differentiation-associated genes. The rise in expression following SUV39H1 knockout concerns mainly genes of the middle/late stage of differentiation and reinforces the differentiation process in comparison to wild-type HaCaT cells | Homo sapiens |
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