Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.1.1.355 extracted from

  • Au Yeung, W.K.; BrindAmour, J.; Hatano, Y.; Yamagata, K.; Feil, R.; Lorincz, M.C.; Tachibana, M.; Shinkai, Y.; Sasaki, H.
    Histone H3K9 methyltransferase G9a in oocytes is essential for preimplantation development but dispensable for CG methylation protection (2019), Cell Rep., 27, 282-293.e4 .
    View publication on PubMed
Search for more literature for 2.1.1.355

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine9 Mus musculus overall reaction 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
-
 ?
S-adenosyl-L-methionine + a [histone H3]-L-lysine9 Mus musculus
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9 Mus musculus
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine9 Mus musculus
-
 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine9
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9Z148
-
-

Source Tissue

Source Tissue Comment Organism Textmining
oocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3 S-adenosyl-L-methionine + a [histone H3]-L-lysine9 overall reaction Mus musculus 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
-
 ?
S-adenosyl-L-methionine + a [histone H3]-L-lysine9
-
 Mus musculus S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine9
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6,N6-dimethyl-L-lysine9
-
 Mus musculus S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine9
-
 ?
S-adenosyl-L-methionine + a [histone H3]-N6-methyl-L-lysine9
-
 Mus musculus S-adenosyl-L-homocysteine + a [histone H3]-N6,N6-dimethyl-L-lysine9
-
 ?

Synonyms

Synonyms Comment Organism
EHMT2
-
 Mus musculus
G9a
-
 Mus musculus
histone H3K9 methyltransferase
-
 Mus musculus

General Information

General Information Comment Organism
physiological function the enzyme regulates chromatin reorganization in mouse oocytes. Maternal enzyme is vital for proper chromosome segregation in preimplantation embryos Mus musculus