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Literature summary for 2.1.1.355 extracted from

  • Ushijima, Y.; Inoue, Y.H.; Konishi, T.; Kitazawa, D.; Yoshida, H.; Shimaji, K.; Kimura, H.; Yamaguchi, M.
    Roles of histone H3K9 methyltransferases during Drosophila spermatogenesis (2012), Chromosome Res., 20, 319-331.
    View publication on PubMed
Search for more literature for 2.1.1.355

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Drosophila melanogaster 5737
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
180000
-
 x * 180000, enzyme form dG9a, SDS-PAGE Drosophila melanogaster

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + histone H3(K9) SETDB1 is mainly responsible for mono- and trimethylation of histone H3 lysine 9 and SU (VAR)3-9 for monomethylation of histone H3 lysine 9 during spermatogenesis Drosophila melanogaster S-adenosyl-L-homocysteine + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 180000, enzyme form dG9a, SDS-PAGE Drosophila melanogaster

Synonyms

Synonyms Comment Organism
dG9a
-
 Drosophila melanogaster
H3K9-specific histone methyltransferase
-
 Drosophila melanogaster
histone H3K9 methyltransferase
-
 Drosophila melanogaster
HMTase
-
 Drosophila melanogaster
SETDB1
-
 Drosophila melanogaster
SU (VAR)3-9
-
 Drosophila melanogaster

General Information

General Information Comment Organism
physiological function SETDB1 is mainly responsible for mono- and trimethylation of histone H3 lysine 9 and SU (VAR)3-9 for monomethylation of histone H3 lysine 9 during spermatogenesis. Enzyme form dG9a plays no apparent role for histone H3 lysine 9 methylation during spermatogenesis and spermiogenesis Drosophila melanogaster