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Literature summary for 2.1.1.348 extracted from
- m(6)A RNA methylation promotes XIST-mediated transcriptional repression (2016), Nature, 537, 369-373 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q86U44 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| METTL3 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | knockdown of methyltransferase like 3 (METTL3) impairs X-inactive specific transcript-mediated gene silencing. X-inactive specific transcript XIST mediates the transcriptional silencing of genes on the X chromosome. YTH domain containing 1 (YTHDC1) preferentially recognizes m6A residues on XIST and is required for XIST function | Homo sapiens |
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Release 2023.1 (January 2023)
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