Literature summary for 2.1.1.348 extracted from

Bartosovic, M.; Molares, H.C.; Gregorova, P.; Hrossova, D.; Kudla, G.; Vanacova, S.
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3-end processing (2017), Nucleic Acids Res., 45, 11356-11370 .

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293 cell	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	METTL3 knockdown leads to a significant downregulation of 3' terminal exons. Demethylase FTO and METTL3 act reciprocally in the regulation of alternative splicing and 3' untranslated region expression	Homo sapiens

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Release 2023.1 (January 2023)