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Literature summary for 2.1.1.346 extracted from

  • Warda, A.S.; Kretschmer, J.; Hackert, P.; Lenz, C.; Urlaub, H.; Hoebartner, C.; Sloan, K.E.; Bohnsack, M.T.
    Human METTL16 is a N6-methyladenosine (m6A) methyltransferase that targets pre-mRNAs and various non-coding RNAs (2017), EMBO Rep., 18, 2004-2014 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + adenine in U6 lncRNA Homo sapiens
-
 S-adenosyl-L-homocysteine + N6-methyladenine in U6 lncRNA
-
 ?
S-adenosyl-L-methionine + adenine in U6 ncRNA Homo sapiens
-
 S-adenosyl-L-homocysteine + N6-methyladenine in U6 ncRNA
-
 ?
S-adenosyl-L-methionine + adenine in U6 pre-mRNA Homo sapiens
-
 S-adenosyl-L-homocysteine + N6-methyladenine in U6 pre-mRNA
-
 ?
S-adenosyl-L-methionine + adenine in U6 snRNA Homo sapiens the enzyme is responsible for N6-methylation of A43 of the U6 snRNA S-adenosyl-L-homocysteine + N6-methyladenine in U6 snRNA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q86W50
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + adenine in U6 lncRNA
-
 Homo sapiens S-adenosyl-L-homocysteine + N6-methyladenine in U6 lncRNA
-
 ?
S-adenosyl-L-methionine + adenine in U6 ncRNA
-
 Homo sapiens S-adenosyl-L-homocysteine + N6-methyladenine in U6 ncRNA
-
 ?
S-adenosyl-L-methionine + adenine in U6 pre-mRNA
-
 Homo sapiens S-adenosyl-L-homocysteine + N6-methyladenine in U6 pre-mRNA
-
 ?
S-adenosyl-L-methionine + adenine in U6 snRNA the enzyme is responsible for N6-methylation of A43 of the U6 snRNA Homo sapiens S-adenosyl-L-homocysteine + N6-methyladenine in U6 snRNA
-
 ?

Subunits

Subunits Comment Organism
? x * 80000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
METTL16
-
 Homo sapiens
N6-methyladenosine (m6A) methyltransferase
-
 Homo sapiens