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Literature summary for 2.1.1.33 extracted from
- The core domain of Aquifex aeolicus tRNA (m7G46) methyltransferase has the methyl-transfer activity to tRNA (2006), Nucleic Acids Symp. Ser., 50, 245-246.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| Glu202Stop | is unstable to heat treatment as compared to the full-length wild-type enzyme, but has an enzymatic activity | Aquifex aeolicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + guanine46 in tRNA | Aquifex aeolicus | - |
S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Aquifex aeolicus | O66479 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + guanine46 in tRNA | - |
Aquifex aeolicus | S-adenosyl-L-homocysteine + N7-methylguanine46 in tRNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| transfer RNA (m7G46) methyltransferase | - |
Aquifex aeolicus |
| TrmB | - |
Aquifex aeolicus |
| tRNA (m7G46) methyltransferase | - |
Aquifex aeolicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | long C-terminal region of the thermophilic TrmB protein is involved in the protein stability but does not function in the RNA recognition | Aquifex aeolicus |
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Release 2023.1 (January 2023)
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