Literature summary for 2.1.1.320 extracted from

Zhang, W.; Zhang, Y.; Zhao, X.; Hua, Y.; Wu, Z.; Yan, Y.; Li, Y.
Prmt7 regulates epiboly by facilitating 2-OST and modulating actin cytoskeleton (2015), J. Mol. Cell Biol., 7, 489-491.

Search for more literature for 2.1.1.320

Organism

Organism	UniProt	Comment	Textmining
Danio rerio	A2AV36	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	Prmt7 transcripts and protein are maternally deposited and ubiquitously expressed through gastrulation	Danio rerio	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 S-adenosyl-L-methionine + [histone H4]-L-arginine	-	Danio rerio	2 S-adenosyl-L-homocysteine + [histone H4]-Nomega,Nomega'-dimethyl-L-arginine	enzyme specifically methylates histone H4 Arg3 to form symmetric dimethylarginines. In addition, it is annotated for formation of omega-N monomethylarginine, reaction of EC 2.1.1.321	?

Synonyms

Synonyms	Comment	Organism
PRMT7	-	Danio rerio

General Information

General Information	Comment	Organism
physiological function	at 10 hours post-fertilization, Prmt7 morphants display an epibolic delay defects phenotype compared with control embryos that have completed epiboly and entirely enclosed the yolk sphere. Both shape and orientation of enveloping layer cells in Prmt7 morphants are altered. In control embryos, enveloping layer cells are elongated and regularly aligned. Enveloping layer cells in Prmt7 morphants are mostly round, small, and irregularly aligned more disorganized and fail to align their cell bodies along the direction of epibolic movement	Danio rerio

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Release 2023.1 (January 2023)