Literature summary for 2.1.1.320 extracted from

Sakai, N.; Saito, Y.; Fujiwara, Y.; Shiraki, T.; Imanishi, Y.; Koshimizu, T.A.; Shibata, K.
Identification of protein arginine N-methyltransferase 5 (PRMT5) as a novel interacting protein with the tumor suppressor protein RASSF1A (2015), Biochem. Biophys. Res. Commun., 467, 778-784.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-
microtubule	coexpression of candidate tumor suppressor gene RASSF1A and PRMT5 leads to a redistribution of PRMT5 from the cytosol to stabilized microtubules	Homo sapiens	5874	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O14744	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PRMT5	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	isoform PRMT5 interacts with candidate tumor suppressor gene RASSF1A. Coexpression of RASSF1A and PRMT5 leads to a redistribution of PRMT5 from the cytosol to stabilized microtubules, where RASSF1A and PRMT5 become colocalized. PRMT5 translocates to bundled microtubules on stabilization by RASSF1A expression	Homo sapiens

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Release 2023.1 (January 2023)