Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] | Streptomyces sp. | - |
S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin] | - |
? | |
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] | Streptomyces sp. OH-4156 | - |
S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces sp. | - |
- |
- |
Streptomyces sp. OH-4156 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + haloduracin | - |
Streptomyces sp. | ? | - |
? | |
S-adenosyl-L-methionine + haloduracin | - |
Streptomyces sp. OH-4156 | ? | - |
? | |
S-adenosyl-L-methionine + L-Lys | the enzyme can also methylate the epsilon-amino group of L-Lys. Peptides with Lys in the first or second position from the N-terminus (entries 9-10) are not modified by the enzyme, but a peptide with a Lys at the C-terminus (entry 11) is methylated, with both di- and tetra-methylated products detected in the reaction mixture | Streptomyces sp. | S-adenosyl-L-homocysteine + N6-methyl-L-lysine | - |
? | |
S-adenosyl-L-methionine + L-Lys | the enzyme can also methylate the epsilon-amino group of L-Lys. Peptides with Lys in the first or second position from the N-terminus (entries 9-10) are not modified by the enzyme, but a peptide with a Lys at the C-terminus (entry 11) is methylated, with both di- and tetra-methylated products detected in the reaction mixture | Streptomyces sp. OH-4156 | S-adenosyl-L-homocysteine + N6-methyl-L-lysine | - |
? | |
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] | - |
Streptomyces sp. | S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin] | - |
? | |
S-adenosyl-L-methionine + N-terminal L-alanine-[cypemycin] | - |
Streptomyces sp. OH-4156 | S-adenosyl-L-homocysteine + N-terminal N,N-dimethyl-L-alanine-[cypemycin] | - |
? | |
S-adenosyl-L-methionine + nisin | - |
Streptomyces sp. | ? | - |
? | |
S-adenosyl-L-methionine + nisin | - |
Streptomyces sp. OH-4156 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha-N-methyltransferase | - |
Streptomyces sp. |
CypM | - |
Streptomyces sp. |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the biosynthesis of the peptide antibiotic cypemycin | Streptomyces sp. |