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Literature summary for 2.1.1.247 extracted from
- Involvement of the A isozyme of methyltransferase II and the 29-kilodalton corrinoid protein in methanogenesis from monomethylamine (1995), J. Bacteriol., 177, 4410-4416.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Methanosarcina barkeri | methylamine-dependent methylation of CoM mediated by trimethyamine- or monomethylamine-specific methyltransferases derived from cells grown on trimethylamine. Methylation of CoM by trimethylamine and methylation by monomethylamine are mediated by separate enzyme systems with at least one different component | ? | - |
? |  |
| additional information | Methanosarcina barkeri MS / DSM 800 | methylamine-dependent methylation of CoM mediated by trimethyamine- or monomethylamine-specific methyltransferases derived from cells grown on trimethylamine. Methylation of CoM by trimethylamine and methylation by monomethylamine are mediated by separate enzyme systems with at least one different component | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanosarcina barkeri | O30640 | isozyme MT2-A | - |
| Methanosarcina barkeri MS / DSM 800 | O30640 | isozyme MT2-A | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture condition:trimethylamine-grown cell | - |
Methanosarcina barkeri | - |
| additional information | numerous extracts of cells grown on methanol do not possess detectable levels of TMA:CoM methyl group transfer activity | Methanosarcina barkeri | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.258 | - |
MMA:CoM methyl transfer from TMA-grown cells, pH and temperature not specified in the publication | Methanosarcina barkeri |
| 0.452 | - |
TMA:CoM methyl transfer from TMA-grown cells, pH and temperature not specified in the publication | Methanosarcina barkeri |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | methylamine-dependent methylation of CoM mediated by trimethyamine- or monomethylamine-specific methyltransferases derived from cells grown on trimethylamine. Methylation of CoM by trimethylamine and methylation by monomethylamine are mediated by separate enzyme systems with at least one different component | Methanosarcina barkeri | ? | - |
? | |
| additional information | methylamine-dependent methylation of CoM mediated by trimethyamine- or monomethylamine-specific methyltransferases derived from cells grown on trimethylamine. Methylation of CoM by trimethylamine and methylation by monomethylamine are mediated by separate enzyme systems with at least one different component | Methanosarcina barkeri MS / DSM 800 | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| methyltransferase II | - |
Methanosarcina barkeri |
| MMA-specific methyltransferase | - |
Methanosarcina barkeri |
| MMA:CoM methyl transferase | - |
Methanosarcina barkeri |
| MT2 | - |
Methanosarcina barkeri |
| MT2-A | - |
Methanosarcina barkeri |
| TMA-specific methyltransferase | - |
Methanosarcina barkeri |
| TMA:CoM methyl transferase | - |
Methanosarcina barkeri |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | isozyme MT2-A functions in methanogenesis from monomethylamine | Methanosarcina barkeri |
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