Crystallization (Comment) | Organism |
---|---|
sitting-drop vapor-diffusion method at 19°C. Crystal structure of TrmI, in complex with S-adenosyl-L-homocysteine, is determined at 1.7 A resolution. The conserved residues that form the catalytic cavity (D170, Y78, and Y194) are essential for fashioning an optimized shape of the catalytic pocket | Thermus thermophilus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | Q8GBB2 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + adenine58 in tRNA | - |
Thermus thermophilus | S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNA | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | the enzyme remains tetrameric upon tRNA binding, with formation of complexes involving one to two molecules of tRNA per TrmI tetramer | Thermus thermophilus |
Synonyms | Comment | Organism |
---|---|---|
m1A58 tRNA methyltransferase | - |
Thermus thermophilus |
TrmI | - |
Thermus thermophilus |
tRNA m1A58 methyltransferase | - |
Thermus thermophilus |