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Literature summary for 2.1.1.216 extracted from

  • Kawamura, T.; Anraku, R.; Hasegawa, T.; Tomikawa, C.; Hori, H.
    Transfer RNA methyltransferases from Thermoplasma acidophilum, a thermoacidophilic archaeon (2014), Int. J. Mol. Sci., 16, 91-113.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.1.1.216

Cloned(Commentary)

Cloned (Comment) Organism
-
 Thermoplasma acidophilum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet Thermoplasma acidophilum m2G26 and m22G26 are formed by Trm1 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet
-
 ?
4 S-adenosyl-L-methionine + guanine26 in prolongator tRNAMet Thermoplasma acidophilum m2G26 and m22G26 are formed by Trm1 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in prolongator tRNAMet
-
 ?
4 S-adenosyl-L-methionine + guanine26 in tRNA Thermoplasma acidophilum G modification at position 26 is a mixture of m2G and m22G generated by Trm1 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA
-
 ?

Organism

Organism UniProt Comment Textmining
Thermoplasma acidophilum
-
-
-
Thermoplasma acidophilum P57706
-
-
Thermoplasma acidophilum HO-62
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Thermoplasma acidophilum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 S-adenosyl-L-methionine + guanine26 in elongator tRNAMet
-
 Thermoplasma acidophilum 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in elongator tRNAMet
-
 ?
2 S-adenosyl-L-methionine + guanine26 in elongator tRNAMet
-
 Thermoplasma acidophilum HO-62 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in elongator tRNAMet
-
 ?
2 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet
-
 Thermoplasma acidophilum 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet
-
 ?
2 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet
-
 Thermoplasma acidophilum HO-62 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet
-
 ?
2 S-adenosyl-L-methionine + guanine26 in tRNALeu(UAG)
-
 Thermoplasma acidophilum 2 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNALeu(UAG)
-
 ?
4 S-adenosyl-L-methionine + guanine26 in initiator tRNAMet m2G26 and m22G26 are formed by Trm1 Thermoplasma acidophilum 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in initiator tRNAMet
-
 ?
4 S-adenosyl-L-methionine + guanine26 in prolongator tRNAMet m2G26 and m22G26 are formed by Trm1 Thermoplasma acidophilum 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in prolongator tRNAMet
-
 ?
4 S-adenosyl-L-methionine + guanine26 in tRNA
-
 Thermoplasma acidophilum 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA
-
 ?
4 S-adenosyl-L-methionine + guanine26 in tRNA G modification at position 26 is a mixture of m2G and m22G generated by Trm1 Thermoplasma acidophilum 4 S-adenosyl-L-homocysteine + N2-dimethylguanine26 in tRNA
-
 ?
additional information the enzyme Trm1 is single site-specific Thermoplasma acidophilum ?
-
 ?
S-adenosyl-L-methionine + guanine26 in elongator tRNAMet
-
 Thermoplasma acidophilum S-adenosyl-L-homocysteine + N2-methylguanine26 in elongator tRNAMet
-
 ?
S-adenosyl-L-methionine + guanine26 in initiator tRNAMet
-
 Thermoplasma acidophilum S-adenosyl-L-homocysteine + N2-methylguanine26 in initiator tRNAMet
-
 ?

Synonyms

Synonyms Comment Organism
Ta0997 locus name Thermoplasma acidophilum
Trm1
-
 Thermoplasma acidophilum
tRNA (guanine(26)-N(2))-dimethyltransferase
-
 Thermoplasma acidophilum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
50
-
 assay at Thermoplasma acidophilum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 assay at Thermoplasma acidophilum

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
 Thermoplasma acidophilum

General Information

General Information Comment Organism
physiological function initiator tRNAMet from Thermoplasma acidophilum contains the m22G26 modification in addition to m2G26, the TrmI activity is responsible for these modifications Thermoplasma acidophilum