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Literature summary for 2.1.1.20 extracted from

  • Ottaviani, S.; Brooke, G.N.; OHanlon-Brown, C.; Waxman, J.; Ali, S.; Buluwela, L.
    Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells (2013), J. Mol. Endocrinol., 51, 301-312.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
BPH-1 cell
-
Homo sapiens
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DU-145 cell
-
Homo sapiens
-
LNCaP cell
-
Homo sapiens
-
LNCaP-C4 cell
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Homo sapiens
-
LNCAP-C4-2B cell
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Homo sapiens
-

Expression

Organism Comment Expression
Homo sapiens GNMT expression is stimulated by androgen in androgen receptor expressing cells, the stimulation occurs at the mRNA and protein levels. Androgen receptor binds to an androgen response element within the first exon of the GNMT gene in vitro and in vivo up