Any feedback?
Literature summary for 2.1.1.180 extracted from
- Sites of action of two ribosomal RNA methylases responsible for resistance to aminoglycosides (1987), J. Mol. Biol., 193, 661-671.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + adenine1408 in 16S rRNA | Streptomyces tenjimariensis | resistance to kanamycin plus apramycin results from conversion of residue adenine1408 to 1-methyladenine | S-adenosyl-L-homocysteine + N1-methyladenine1408 in 16S rRNA | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Streptomyces tenjimariensis | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine + adenine1408 in 16S rRNA | resistance to kanamycin plus apramycin results from conversion of residue adenine1408 to 1-methyladenine | Streptomyces tenjimariensis | S-adenosyl-L-homocysteine + N1-methyladenine1408 in 16S rRNA | - |
? | |
| S-adenosyl-L-methionine + adenine1408 in 16S rRNA | precise location of methylation site | Streptomyces tenjimariensis | S-adenosyl-L-homocysteine + N1-methyladenine1408 in 16S rRNA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| kanamycin-apramycin resistance methylase | - |
Streptomyces tenjimariensis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | resistance to kanamycin plus apramycin results from conversion of residue adenine1408 to 1-methyladenine | Streptomyces tenjimariensis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
