BRENDA - Enzyme Database
show all sequences of 2.1.1.174

Ribosomal RNA guanine-(N2)-methyltransferases and their targets

Sergiev, P.V.; Bogdanov, A.A.; Dontsova, O.A.; Nucleic Acids Res. 35, 2295-2301 (2007)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
Escherichia coli
-
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Escherichia coli
Q0T0I4
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
-
689247
Escherichia coli
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
-
-
-
?
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
RlmG possessing an additional RNA-binding domain act on naked ribosomal RNA or early assembly intermediates in the cell
689247
Escherichia coli
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
ribosomal RNA large subunit methyltransferase G
-
Escherichia coli
RlmG
-
Escherichia coli
ygjO
-
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
Escherichia coli
-
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
-
689247
Escherichia coli
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
-
-
-
?
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
RlmG possessing an additional RNA-binding domain act on naked ribosomal RNA or early assembly intermediates in the cell
689247
Escherichia coli
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
-
-
-
?
General Information
General Information
Commentary
Organism
malfunction
lack of G1835 methylation in rlmG(ygjO) knockout strain does not lead to significant growth retardation at the optimal growth conditions. However, in the poor medium and at elevated temperature, the rlmG(ygjO) knockout strain has significantly decreased fitness
Escherichia coli
General Information (protein specific)
General Information
Commentary
Organism
malfunction
lack of G1835 methylation in rlmG(ygjO) knockout strain does not lead to significant growth retardation at the optimal growth conditions. However, in the poor medium and at elevated temperature, the rlmG(ygjO) knockout strain has significantly decreased fitness
Escherichia coli
Other publictions for EC
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721034
Zhang
Structural insights into the f ...
Escherichia coli
RNA
18
1500-1509
2012
-
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1
1
1
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-
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2
-
1
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1
-
-
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2
2
3
-
-
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-
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-
1
-
-
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1
1
1
1
-
-
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2
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2
2
-
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2
2
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-
719013
Osterman
Methylated 23S rRNA nucleotide ...
Escherichia coli
Biochimie
93
725-729
2011
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-
-
-
1
-
-
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-
1
-
1
-
3
-
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2
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1
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1
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1
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1
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2
-
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-
-
-
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2
2
-
-
-
689247
Sergiev
Ribosomal RNA guanine-(N2)-met ...
Escherichia coli
Nucleic Acids Res.
35
2295-2301
2007
-
-
-
-
-
-
-
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-
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1
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1
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2
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1
1
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675412
Sergiev
Identification of Escherichia ...
Escherichia coli
J. Mol. Biol.
364
26-31
2006
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1
-
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-
1
1
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2
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1
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2
1
3
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1
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1
1
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1
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2
1
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1
1
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