Literature summary for 2.1.1.17 extracted from

Tajuddin, S.M.; Amaral, A.F.; Fernandez, A.F.; Chanock, S.; Silverman, D.T.; Tardon, A.; Carrato, A.; Garcia-Closas, M.; Jackson, B.P.; Torano, E.G.; Marquez, M.; Urdinguio, R.G.; Garcia-Closas, R.; Rothman, N.; Kogevinas, M.; Real, F.X.; Fraga, M.F.; Malats, N.; Malats, N.
LINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk (2014), Br. J. Cancer, 110, 2123-2130.

Search for more literature for 2.1.1.17

Application

Application	Comment	Organism
medicine	both low and high levels of global DNA methylation are associated with the risk of bladder cancer. This risk follows a nonlinear association with LINE-1 methylation which significantly increases among individuals homozygous for the major allele of five single-nucleotide polymorphisms located in the phosphatidylethanolamine N-methyltransferase gene	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)