Cloned (Comment) | Organism |
---|---|
a LLC-PK1 cell line stably expressing PEMT shorter isoform (LLC-PK1 /PEMT) is established | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
19000 | - |
SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9UBM1 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
PEMT shorter isoform | - |
Homo sapiens |
phosphatidylethanolamine N-methyltransferase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | expression of PEMT increases the cellular phosphatidylcholine (PC) content, lowers the phosphatidylethanolamine (PE) content, but has no effect on the sphingomyelin content. Consequently, PEMT expression leads to reductions in PE/PC and sphingomyelin /PC ratios. PEMT expression enhances the resistance to duramycin and lysenin. PEMT expression increases the diameter of microvilli. The expression of PEMT results in reduced resistance to unconjugated bile salts, but in increased resistance to conjugated bile salts | Homo sapiens |